Mikhael Antone was born and raised in Cumberland, Rhode Island a small suburb of Providence, RI. After completing her BA at Salve Regina University in philosophy and studio art, she moved to New York with an AmeriCorps Grant to teach Art at an all girl high school in Flatbush, Brooklyn. After living in a former orphanage for a year, she attended School of Visual Arts to study Experimental Video and Photography graduating in 2002. Mikhael has both exhibited and or screened work in New York at Anthology Film Archives, Void, Remote Lounge, BAM Rose cinemas, Praxis Collective, Studio 150, and the College of Staten Island and nationally in Newport, Rhode Island, Houston, Texas and Denver, CO among others.

Currently, Mikhael is an adjunct professor of photography and film production at the College of Staten Island: CUNY. Mikhael lives and works in Staten Island, NY.